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The aim of the present study was to assess the level of self-esteem and Hope among HIV positive Adolescents across gender. The researcher considered perinatally infected Adolescent boys and girls who are HIV Positive, currently living in a HIV care and support centre. The permission for the study was taken from the organisation head of the respective HIV care and support Home. The study adopts a quasi-experimental non-equivalent control group design. A purposive sample of 98 adolescent boys and girls were selected. It was hypothesized that there is no difference in the level of hope and Self-esteem among boys and girls. The participants were assessed using Rosenberg’s Self Esteem Scale and Children’s Hope Scale. The results were analyzed using t and Mann Whitney U test for independent means. The results reveal that adolescents with HIV Positive have low level of self-esteem and hope. There is no significant difference between boys and girls on self-esteem. Examination of means on hope shows that mean for boys is significantly higher than the mean for girls, which shows that boys have significantly higher hope when compared to girls.

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